Genetics Meets Metabolomics

from Experiment to Systems Biology

Buch | Hardcover

318 Seiten

2012 | 2012
Springer-Verlag New York Inc.
978-1-4614-1688-3 (ISBN)

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This book is written by leading researchers in the fields about the intersection of genetics and metabolomics which can lead to more comprehensive studies of inborn variation of metabolism.

Introduction.- Pre-conditions for high quality biobanking in large human epidemiological cohorts for metabolomics and other -omics studies.- Assay Tools for Metabolomics.- Statistical methods in genetic and molecular epidemiology and their application in studies with metabolic phenotypes.- Ultrahigh resolution mass spectrometry based non-targeted microbial metabolomics.- etabolomic systems biology of protozoan parasites.- Mouse genetics and metabolic mouse phenotyping.- Metabolomics in animal breeding.- Metabolomics applications in human nutrition.- Metabolomics for the individualized therapy of androgen deficiency syndrome in male adults.- Systems biology resources arising from the human metabolome project.- Understanding cancer metabolism through global metabolomics.- Genetic and metabolic determinants of fatty acid chain length and desaturation, their incorporation into lipid classes and their effects on risk of vascular and metabolic disease.- Mapping metabolomic quantitative trait loci (mQTL) – A link between metabolome-wide association studies and systems biology.- Metabolic traits as intermediate phenotype.- Genome-wide association studies with metabolomics.- Systems biology meets metabolism.- Index.

Erscheint lt. Verlag	2.7.2012
Zusatzinfo	XVIII, 318 p.
Verlagsort	New York, NY
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Informatik ► Weitere Themen ► Bioinformatik
	Medizin / Pharmazie ► Medizinische Fachgebiete
	Studium ► 1. Studienabschnitt (Vorklinik) ► Biochemie / Molekularbiologie
	Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik
	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	Humangenetik
ISBN-10	1-4614-1688-4 / 1461416884
ISBN-13	978-1-4614-1688-3 / 9781461416883
Zustand	Neuware