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Dopamine in the Pathophysiology and Treatment of Schizophrenia -

Dopamine in the Pathophysiology and Treatment of Schizophrenia

New Findings

Shitij Kapur, Yves Lecrubier (Herausgeber)

Buch | Softcover
272 Seiten
2003 | 2nd New edition
CRC Press (Verlag)
978-1-84184-304-9 (ISBN)
CHF 94,25 inkl. MwSt
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A review of research on the role of dopamine in the etiology and clinical presentation of schizophrenia and in the mechanism of action of antipsychotic drugs.
Covering the latest advances in the field, Dopamine in the Treatment of Schizophrenia, Second Edition provides a detailed explanation of the etiology and clinical presentation of the disease, especially as related to the dopamine system. Written by an international team of experts, the text identifies genetic polymorphisms that affect dopaminergic neurotransmission and their possible impact on familial forms of schizophrenia. It also explores the neurophysiological and neurochemical studies of dopaminergic function and the integration of dopamine-containing neurons with other transmitter systems. It reviews imaging studies and their contribution to our understanding of the pathophysiology of schizophrenia and the mechanism of action of antipsychotics. Finally, the book puts the role of dopamine in the context of other brain systems and highlights the many unmet needs of patients, despite best current treatments.

Historical Aspects and Future Directions
Evidence of Brain Imaging Studies for Dopaminergic Alterations in Schizophrenia
Modulation of Dopamine D^O2
Receptors as a Basis of Antipsychotic Effect
Amisulpride as a Model: Clinical Effects of a Pure Dopaminergic Agent
A Meta-analysis of Studies with the Atypical Antipsychotic Amisulpride
Evidence from Brain Imaging fpr Regional Monoaminergic Specificity in Schizophrenia
Dopamine, the Prefrontal Cortex, and A Genetic Mechanism of Schizophrenia
Models of Schizophrenia: From Neuroplasticity and Dopamine to Psychopathology and Clinical Management
Multiple Neurotransmitters Involved in Antipsychotic Drug Action
Dopaminergic and Glutamatergic Influences in the Systems Biology of Schizophrenia
Pharmacogenomics of Antipsychotic Drugs
Key Issues and Unmet Needs in Schizophrenia
Index

Erscheint lt. Verlag 12.9.2003
Zusatzinfo 82 Illustrations, black and white
Verlagsort London
Sprache englisch
Maße 156 x 235 mm
Gewicht 644 g
Themenwelt Geisteswissenschaften Psychologie Klinische Psychologie
Medizin / Pharmazie Medizinische Fachgebiete Neurologie
Medizin / Pharmazie Medizinische Fachgebiete Psychiatrie / Psychotherapie
Studium 2. Studienabschnitt (Klinik) Pathologie
ISBN-10 1-84184-304-0 / 1841843040
ISBN-13 978-1-84184-304-9 / 9781841843049
Zustand Neuware
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