Practice of Medicinal Chemistry (eBook)

David Aldous, Pierre Raboisson, Didier Rognan, Camille Georges Wermuth (Herausgeber)

eBook Download: PDF | EPUB

2015 | 4. Auflage
902 Seiten
Elsevier Science (Verlag)
978-0-12-417213-5 (ISBN)

Infos

The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough  treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.

With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development.

• Includes updated and expanded material on systems biology, chemogenomics, computer-aided drug design, and other important recent advances in the field
• Incorporates extensive color figures, case studies, and practical examples to help users gain a further understanding of key concepts
• Provides high-quality content in a comprehensive manner, including contributions from international chapter authors to illustrate the global nature of medicinal chemistry and drug development research
• An image bank is available for instructors at www.textbooks.elsevier.com

Textauszug

List of Contributors

Anne Badel,     UMR-S973, MTi, University Paris Diderot, Paris, France

Patrick Bazzini,     PC SAS, Bd Gonthier d’Andernach, Illkirch, France

Frans M. Belpaire,     Heymans Institute for Pharmacology, Gent, Belgium

Alexandre Borrel

University of Helsinki, Helsinki, Finland

UMR-S973, MTi, University Paris Diderot, Paris, France

Koen Boussery,     Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Gent University, Gent, Belgium

Christopher Brice,     Consultant, Luthi & Co., Intellectual Property Law Offices, of Tel Aviv, Israel

Anne-Claude Camproux,     UMR-S973, MTi, University Paris Diderot, Paris, France

David Cavalla,     Numedicus Ltd, Cambridge, England

Paola Ciapetti,     Head of Medicinal Chemistry, Novalyst Discovery, Illkirch, Cedex, France

Hongming Chen,     Chemistry Innovation Centre, Discovery Sciences, AstraZeneca R&D, Mölndal, Sweden

Yong Mi Choi-Sledeski,     Sanofi, Boston, MA, USA

Bernd Clement,     Pharmaceutical Institute, Christian Albrechts-University, Gutenbergstraße, Kiel, Germany

Gordon M. Cragg,     NIH Special Volunteer, Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, United States National Cancer Institute, Frederick, Maryland, USA

Patrick M. Dansette,     Laboratoire de Chimie et Biochimie Pharmacologique et Toxicologique, Université Paris Descartes, Sorbonne Paris Cité, Paris

Pierre deMontigny,     Sanofi, Waltham, MA, U.S.A

Ji-Cui Dong,     INN Programme, World Health Organization, Geneva Essential Medicines and Health Products, Regulation of Medicines and Other Health, Technologies, Technologies Standards and Norms

Iain G. Dougall,     IGD Consultancy Ltd, Loughborough, Leics, UK

Ola Engkvist,     Chemistry Innovation Centre, Discovery Sciences, AstraZeneca R&D, Mölndal, Sweden

Bernard Faller,     Novartis Pharma AG, Werk Klybeck Klybeckstrasse, Basel, Switzerland

Bennett T. Farmer,     Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT, USA

Delphine Flatters,     UMR-S973, MTi, University Paris Diderot, Paris, France

Bruno Galli,     Novartis Pharma AG, Lichtstrasse, Basel, Switzerland

Colette Geneix,     UMR-S973, MTi, University Paris Diderot, Paris, France

Bruno Giethlen,     Novartis Pharma AG, Basel, Switzerland

Serge Grisoni,     Pierre Fabre Research Institute, Toulouse, Cédex, France

Gerhard Gross,     Scientific Director at Janssen in Beerse, Belgium

David Harris,     Sanofi, Waltham, MA, U.S.A

Yuichi Hashimoto,     Institute of Molecular and Cellular Biosciences, The University of Tokyo, Japan

Chris Ho,     Sanofi, Waltham, MA, U.S.A

Andrew L. Hopkins,     College of Life Sciences, University of Dundee, Dundee, Scotland, UK

Hiba Abi Hussein,     UMR-S973, MTi, University Paris Diderot, Paris, France

Peter Imming,     Institut fuer Pharmazie, Martin-Luther-Universitaet Halle-Wittenberg, Halle, Germany

Minoru Ishikawa,     Institute of Molecular and Cellular Biosciences, The University of Tokyo, Japan

Tim Jonckers,     Janssen Research & Development Janssen Infectious Diseases – Diagnostics BVBA, Turnhoutseweg, Beerse, Belgium

Sabine Kopp,     World Health Organization, Geneva Essential Medicines and Health Products, Regulation of Medicines and Other Health, Technologies, Technologies Standards and Norms

David G.I. Kingston,     Department of Chemistry and the Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia, USA

Thierry Kogej,     Chemistry Innovation Centre, Discovery Sciences, AstraZeneca R&D, Mölndal, Sweden

Sophie Lasseur,     INN Programme, World Health Organization, Geneva Essential Medicines and Health Products, Regulation of Medicines and Other Health, Technologies, Technologies Standards and Norms

Dominique Lesuisse,     Lead Generation Board, Sanofi, AVENUE PIERRE BROSSOLETTE, CHILLY MAZARIN - France

Harvey Lieberman,     Sanofi, Waltham, MA, USA

Richard Luthi,     Founding partner, Luthi & Co., Intellectual Property Law Offices, of Tel Aviv, Israel

Anne-Christine Macherey,     Prévention du Risque Chimique, Gif sur Yvette, France

André Mann,     LAAS-CNRS, Université Louis Pasteur, Strasbourg, France

Raffaella G. Balocco Mattavelli,     INN Programme, World Health Organization, Geneva Essential Medicines and Health Products, Regulation of Medicines and Other Health, Technologies, Technologies Standards and Norms

Christophe Morice,     Prestwick Chemical Inc., Boulevard Gonthier, Illkirch, France

Richard Morphy,     Eli Lilly, Erl Wood Manor, Windlesham, Surrey, UK

David J. Newman,     NIH Special Volunteer, Natural Products Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, United States National Cancer Institute, Frederick, Maryland, USA

Anne Olivier,     Sanofi-Aventis Recherche et Développement, Chilly-Mazarin, France

Michel Petitjean,     UMR-S973, MTi, University Paris Diderot, Paris, France

Pierre Raboisson,     Janssen Infectious Diseases and Diagnostics BVBA, Beerse, Belgium

Zoran Rankovic,     Eli Lilly, Indianapolis, IN, USA

Leslie Regad,     UMR-S973, MTi, University Paris Diderot, Paris, France

Allen B. Reitz,     Fox Chase Chemical Diversity Center, Inc., Doylestown, PA, USA

Bernd U. Riebesehl,     Technical Research & Development, Novartis Pharma AG, Basel, Switzerland

Jean-Philippe Rocher,     Pierre Fabre Research Institute, Castres, France

Tiago Rodrigues,     Swiss Federal Institute of Technology (ETH), Department of Chemistry and Applied Biosciences, Zürich, Switzerland

A. Romeo,     INN Programme, World Health Organization, Geneva Essential Medicines and Health Products, Regulation of Medicines and Other Health, Technologies, Technologies Standards and Norms

Jean-Michel Rondeau,     Novartis Institutes for BioMedical Research, Basel, Switzerland

Laurent Schaeffer,     Prestwick Chemical Inc., Boulevard Gonthier, Illkirch, France

Jean-Michel Scherrmann,     Department of Pharmaceutical Sciences, University Paris...

Produkt-Details

• Erscheint lt. Verlag: 1.7.2015
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• ISBN-10: 0-12-417213-X / 012417213X
• ISBN-13: 978-0-12-417213-5 / 9780124172135