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Essentials of Blood Product Management in Anesthesia Practice -

Essentials of Blood Product Management in Anesthesia Practice

Buch | Hardcover
XVII, 478 Seiten
2021 | 1st ed. 2021
Springer International Publishing (Verlag)
978-3-030-59294-3 (ISBN)
CHF 249,95 inkl. MwSt
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This comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice.

Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. Essentials of Blood Product Management in Anesthesia Practice is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.

Corey Scher MD Clinical Professor of Anesthesiology New York University School of Medicine Bellevue Hospital Center New York, NY Alan David Kaye MD, PhD Vice-Chancellor of Academic Affairs, Chief Officer, and Provost Tenured Professor, Departments of Anesthesiology and Pharmacology, Toxicology, and Neurosciences LSU School of Medicine Shreveport, LA USA Henry Liu MD Professor of Anesthesiology & Perioperative Medicine Milton S. Hershey Medical Center Penn State University College of Medicine Hershey, PA USA Seth Perleman MD Associate Professor of Anesthesiology New York University School of Medicine Langone Medical Center New York University School of Medicine New York, NY USA Sarah Leavitt MD Assistant Professor Department of Anesthesiology NYU Langone Medical Center Bellevue HospitalNew York, NY USA

The History of Blood Transfusions

Modern Blood Banking

Component Therapy and Whole Blood: Packed Red Blood Cells, Fresh Frozen Plasma, Cryoprecipitate, washed and or radiated red cells

The Coagulation System and Clot Stability

Fibrinolysis- Tranexamic Acid and Aminocaproic Acid.

Hypercoagulation and Thrombotic Disorders: TTP, Factor 5 Leiden, Phospholipid Syndrome, Anti-thrombin 3, hypereosinophils, oxidative stress, cancer.

Diseases or Conditions of Platelet Dysfunction

The Massive Transfusion Protocol

New Biologicals to Assist Clotting- Riastap, Prothrombin Concentrates. Antithrombin3, Fibrogammin and factor13, Fibrosupernatant, Fibrinogen Concentrates, Recombinant Factor 7, DDAVP, Octaplast G., Factor 10A, KCentra

Biologicals that Inhibit Clot generation -The Heparins, Factor 10A inhibitors, rivaroxaban, apixaban, dabigatran,

Point of Care Testing and Goal Directed Therapy- Thromboelastography, ROTEM, Platelet function analyzer, stat-PT, thrombin generation assays, multi-electro-aggregometry, OHP (Overall hemostatic potential assay), ACT.

Complications of Blood Transfusions: TRALI, TACO, Blood type mismatch, infection

Diseases of the Coagulation System- Hemophilia, VonWillebrand Disease, Cryoglobulinemia, Inborn Errors of Factor Synthesis

Blood Conservation Strategies and Bloodless Surgery- normovolemic hemodilution, cell saver,

Bridges to Transfusion when blood is not immediately available.

Artificial Blood

Preoperative correction of anemia

Blood Deployment in Natural Disasters and the Military in Combat

Commonly prescribed medications that affect clotting-anti-depressants, NSAIDS, ASA

Anesthesia for the severe trauma patient- new evidence from new trials

Old blood vs. new blood- Is storage injury a concern?

Vascular Endothelial dysfunction and inflammatory states

Liberal or restrictive blood transfusions

Erscheinungsdatum
Zusatzinfo XVII, 478 p. 71 illus., 61 illus. in color.
Verlagsort Cham
Sprache englisch
Maße 210 x 279 mm
Gewicht 1669 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Anästhesie
Medizin / Pharmazie Medizinische Fachgebiete Chirurgie
Medizinische Fachgebiete Innere Medizin Hämatologie
Schlagworte Blood homeostasis • fibrinolysis • Hemoglobin proteins • Point of Care tests for blood clotting • Synthetic clotting factors • thrombosis
ISBN-10 3-030-59294-4 / 3030592944
ISBN-13 978-3-030-59294-3 / 9783030592943
Zustand Neuware
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